When sourcing research peptides, purity is the single most important factor that determines the reliability of your experimental results. But how is purity actually measured, and what should you look for?
What is HPLC?
High-Performance Liquid Chromatography (HPLC) is the industry standard method for analyzing peptide purity. It separates a peptide sample into its individual components, allowing precise measurement of the target compound versus any impurities.
Reading a Certificate of Analysis
A proper COA should include the HPLC chromatogram, the calculated purity percentage, molecular weight confirmation via Mass Spectrometry, and the date of analysis. At Diamond Peptides, every batch ships with this documentation.
Why 99% Matters
Even a 1-2% difference in purity can introduce variables that affect research outcomes. Impurities may include truncated sequences, deletion peptides, or residual solvents — all of which can confound results.
At Diamond Peptides, we hold every compound to a minimum of 98% purity, with most exceeding 99%. This commitment ensures your research starts on solid ground.